Searching for drug synergy in complex dose response landscapes using an interaction potency model

關於「Searching for drug synergy in complex dose response landscapes using an interaction potency model」標籤，搜尋引擎有相關的訊息討論：

Searching for Drug Synergy in Complex Dose-Response ... - PubMed2015年9月25日 · Searching for Drug Synergy in Complex Dose-Response Landscapes Using an Interaction Potency Model. Comput Struct Biotechnol J. 2015 ... twSearching for Drug Synergy in Complex Dose–Response ...Searching for Drug Synergy in Complex Dose–Response Landscapes Using an Interaction Potency Model. Bhagwan Yadav, Krister Wennerberg, Tero ... tw圖片全部顯示Drug synergy scoring using minimal dose response matrices | BMC ...2021年1月19日 · Overall, the optimisation of drug synergy scoring as presented here could inform ... is by using dose–response matrices in disease-appropriate models, ... Yadav B , Wennerberg K, Aittokallio T, Tang J. Searching for drug synergy in complex dose-response landscapes using an interaction potency model. twSystematic measurement of combination drug landscapes to predict ...2021年2月6日 · Drug combination dose response measurements ... We observed a strong dependency in drug potency on in vitro model (Fig. 1A, inhibitory ...Additive Dose Response Models: Defining Synergy | bioRxiv2019年7月31日 · Searching for Drug Synergy in Complex Dose-Response Landscapes Using an Interaction Potency Model. Comput. Struct. Biotechnol.Comparison of null models for combination drug therapy reveals ...2019年2月28日 · Null models for the effect of combination therapies are widely used to evaluate synergy and antagonism of drugs. ... Being an indicator of zero interaction, the isobole separates the plane ... The potency ratio is the ratio of the equipotent doses of two drugs, ... Let us contrast this finding with the Loewe model.Drug and disease signature integration identifies synergistic ...2018年12月14日 · Here, the authors introduce a platform to identify synergistic drug combinations for ... radiation and TMZ treatment clinically has prompted many groups to search for ... The Bliss model, a widely utilized model in synergism studies, ... in complex dose–response landscapes using an interaction potency model.Additive Dose Response Models: Defining Synergy ... - Frontiers2019年11月26日 · A non-interactive response is based on a principle of no interaction, such as ... Another way to quantify synergy on the basis of the isobole is to look at the ... more complex than computing the difference between the raw data and the ... Doseâ€"Response Landscapes Using an Interaction Potency Model. | Efficient measurement and factorization of high-order drug ...2017年10月11日 · In synergistic or antagonistic drug interactions, drugs in combination may be ... TB treatment remains difficult, and combinations of three or more ... the two-drug dose response is the expected dose in the null model (e1; ... with approximately double or half the potency of the single drugs. ... Facebook · Twitter ...